Mycobacterium leprae is an intracellular, pleomorphic, non-sporing, non-motile, acid-fast, pathogenic bacterium. It is an aerobic bacillus (rod-shaped bacterium) with parallel sides and … 詳細

The reductive evolution experienced by the Mycobacterium leprae genome has impaired its metabolic abilities in comparison to other … 詳細

The bacterium has a global distribution in humans but the highest prevalence is in sub-Saharan Africa, Asia and South America. The geographic occurrences of Mycobacterium leprae … 詳細

The incubation period of Mycobacterium leprae ranges from 9 months to 20 years. The bacterium replicates intracellularly inside histiocytes and nerve cells and has two forms. One form is … 詳細

Mycobacterium leprae has a narrow host range and apart from humans the only other hosts are nine-banded armadillos and red squirrels, … 詳細

The first genome sequence of a strain of Mycobacterium leprae was completed in 2001, revealing 1604 protein-coding genes and another 1,116 pseudogenes. The genome sequence of a strain originally isolated in Tamil Nadu, India, and designated TN, was … 詳細

The closest relative to Mycobacterium leprae is Mycobacterium lepromatosis. These species diverged 13.9 million years ago (95% highest posterior density 8.2 million years ago – 詳細