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  1. Landscape of immune cells in systematic lupus ...

  2. Molecular pathways identified from single nucleotide ...

  3. People also ask
    In the prototypic systemic autoimmune disease systemic lupus erythematosus (SLE), monogenic disease accounts for a small fraction of cases but has been instrumental in the elucidation of disease mechanisms.
    Systemic lupus erythematosus (SLE) (OMIM:152700) is a complex autoimmune disease characterized by clinical and genetic heterogeneity. Individuals of East Asian ancestry (AsA) have a greater prevalence of renal involvement, infections and cardiovascular complications compared to individuals of European ancestry (EA) 1.
    Several reports suggest that age-associated B cell (ABC) phenotypes are expanded in patients with systemic lupus erythematosus (SLE) compared with controls.
    Immunochip-based association analyses have identified 700 single-nucleotide polymorphisms (SNPs) reported as significantly associated with SLE in patients of East Asian (AsA) ancestry 6 and 757 SNPs associated with disease in European (EA) populations (Fig. 1 A) 8. Twenty SNP associations (< 1.5%) were shared between ancestries.
  4. Genetics of SLE: mechanistic insights from monogenic ...

  5. 【楽天市場】SLE-1ALMNの通販

  6. Restoration of aberrant gene expression of monocytes in ...

  7. Systemic Lupus Erythematosus Patients with DNASE1L3 ...

  8. Cytokines in Systemic Lupus Erythematosus—Focus on TNF ...

  9. NR_103776.1 as a novel diagnostic biomarker for systemic ...

  10. Managing infections: systemic lupus erythematosus patients ...

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