Distinct ontogenetic lineages dictate cDC2 heterogeneity
WebFeb 13, 2024 · Discussion. Distinct cell types or different cell states can contribute to the heterogeneity of cDC2s. In this study, we identified pre-cDC2s in mouse bone marrow and peripheral tissues that ...
Dendritic cells as orchestrators of anticancer immunity and ...
WebFeb 7, 2024 · Dendritic cells (DCs) are antigen-presenting cells that function at the interface between innate and adaptive immunity, thereby acting as key mediators of antitumour immune responses and ...
Lung cDC1 and cDC2 dendritic cells priming naive CD8
WebOct 20, 2023 · Si et al. show that intranasal nanofiber immunization cross-primes naive CD8+ T cells in the lung before lymph nodes. In the absence of cDC1, cDC2 are sufficient for cross-priming. While lung cDC1 and cDC2 have distinct transcriptional responses, they converge into shared transcriptional responses in the lymph node.
A new step in understanding mouse cDC ontogeny - Nature
WebFeb 13, 2024 · Understanding the ontogeny of conventional dendritic cells (cDCs) is a major aim in the field. The fate of progenitors of the recently described subsets of mouse cDC2s (cDC2A and cDC2B) is ...
Migratory CD103+CD11b+ cDC2s in Peyer’s patches are ...
WebMar 15, 2024 · INTRODUCTION The regulation of immune responses in Peyer’s patches (PP) is still poorly understood and, in particular, the specific functions of dendritic cell (DC) subsets have been incompletely investigated. 1, 2 DCs are critical for the induction of tolerance and immunoglobulin (Ig)A-mediated immunity, which are key elements in …
Q&A（よくある質問）：クリーニングクロスを買い替えたい ...
WebJun 19, 2023 · 以下のクリーリングクロスをお買い求めください。. CD-CC2BLN (ブルー) CD-CC2GN (グリーン) CD-CC23BL (ブルー) CD-CC23G (グリーン) CD-CC24BL (ブルー) CD-CC24G (グリーン) ※添付のクリーニングクロスと同様にご利用いただけます。. 対象カ …
サンワサプライ クリーニングクロス CD-CC2BLN ブルー - OA ...
WebApr 3, 2024 · サンワサプライ クリーニングクロス CD-CC2BLN ブルー ブランド: Oscgws お気に入りブランド クチコミ評価 5.4 （ 535 件） 販売価格 ： ￥ 3,918 税込 獲得ポイント ： 535ポイント カートに入れる お気に入り 175 商品がカートに追加されました ...
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Targeting the Cdc2‐like kinase 2 for overcoming platinum ...
WebApr 13, 2024 · MedComm is a multidisciplinary open access journalpublishing pioneering medical science advances that will improve human health.
Conventional dendritic cell 2 links the genetic causal ...
WebFeb 4, 2024 · Recent evidence suggests that allergic asthma (AA) decreases the risk of Coronavirus Disease 2019 (COVID-19). However, the reasons remain unclear. Here, we systematically explored data from GWAS (18 cohorts with 11,071,744 samples), bulk transcriptomes (3 cohorts with 601 samples), and single-cell transcriptomes (2 cohorts …
Frontiers | Microenvironmental and cell intrinsic factors ...
WebJul 18, 2023 · 2.2 Blood cDC2s can be induced to differentiate into KLF4 hi moDCs and macrophages Since we previously observed that KLF4 is upregulated upon moDC and macrophage differentiation of CD14 + monocytes in response to GM-CSF/IL-4 and M-CSF/IL-6, respectively (), we asked whether KLF4 can be induced in blood cDC2s in …
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