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  1. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK535405

    Systemic Lupus Erythematosus - StatPearls - NCBI …

    WEBAug 4, 2023 · Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild …

    • Author: Angel A. Justiz Vaillant, Amandeep Goyal, Pankaj Bansal, Matthew Varacallo
    • Published: 2023/08/04
    • Publish Year: 2021
  2. 昭和大学リウマチ・膠原病内科
    http://showa-u-rheum.com/2023/10/5073

    欧州リウマチ学会（EULAR）SLE治療推奨2023 | 昭和大学病院 ...

  3. People also ask
    What is systemic lupus erythematosus (SLE)?
    Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement. Several immunopathogenic pathways play a role in the development of SLE.

    Systemic Lupus Erythematosus - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    Can IL-17 be used to treat SLE?
    As SLE is a complex heterogeneous disease with different cytokines involved in its pathogenesis, it is highly unlikely that inhibition of only one molecule, such as IL-17, will be effective in the treatment of all clinical manifestations. Future studies should identify SLE patients that are eligible for Th17-targeted therapy.

    Is Th17-Targeted Therapy Effective in Systemic Lupus Erythematosus?

    pubmed.ncbi.nlm.nih.gov
    Are basophils involved in systemic lupus erythematosus (SLE)?
    Basophils have been implicated in systemic lupus erythematosus (SLE), as evidenced by the fact that basophil-deficient mice do not develop the disease. Here, the authors demonstrate that PD-L1 and IL-4 expression in basophils promotes the pathogenic accumulation of follicular helper T cells in patients with SLE and murine models.

    PD-L1- and IL-4-expressing basophils promote pathogenic ... - Nature

    nature.com
    What if complement levels are low in patients with SLE?
    Complements C3 and C4 shall be checked in patients with SLE or suspicion of SLE, and low complement levels indicate complement consumption and may correlate with disease activity. Markers of inflammation such as erythrocyte sedimentation rate and C-reactive protein may be elevated.

    Systemic Lupus Erythematosus - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
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  4. BMJ Best Practice
    https://bestpractice.bmj.com/crawler/topics/en-gb/103

    Symptoms, diagnosis and treatment - BMJ Best Practice

  5. メディカルノート
    https://medicalnote.jp/contents/161031-0…

    全身性エリテマトーデス（SLE）の治療の選択肢と日 …

    WEBDec 8, 2023 · 全身性エリテマトーデス （ SLE ）の薬物治療では、副腎皮質ホルモンというステロイドが中心であり、主にプレドニゾロンという薬を使うことが多くなっています。 ステロイドが使われる前の死亡率は今よりも高く、4割を超えていたとされていますが、ステロイドをきちん …

  6. Nature
    https://www.nature.com/articles/s41467-024-47691-w

    PD-L1- and IL-4-expressing basophils promote pathogenic ...

  8. Medical DOC(メディカルドック)
    https://medicaldoc.jp/news/news-202402n0706

    【世界初】｢全身性エリテマトーデス｣発症メカニズムを一部 ...

  9. メディカルノート
    https://medicalnote.jp/contents/161031-0…

    全身性エリテマトーデス（SLE）とはどのような病 …

    WEBDec 8, 2023 · 全身性エリテマトーデス （ SLE ）は全身に起こる 自己免疫疾患 の一種で、顔に特徴的な 湿疹 しっしん がみられることが知られています。 全身性エリテマトーデス（SLE）の症状や診断、治療に対する考え方などについて、国立病院機構 横浜医療センター 膠原病 ・リウマチ …

  10. iroiro-nurse.net
    https://iroiro-nurse.net/sle-assessment

    全身性エリテマトーデス（SLE）患者への支援内容とは：訪問 ...

  11. Springer
    https://link.springer.com/article/10.1007/s10528-023-10600-9

    Association of Toll-Like Receptor 7 (TLR7) Polymorphisms with ...

  12. PubMed
    https://pubmed.ncbi.nlm.nih.gov/37232744

    Is Th17-Targeted Therapy Effective in Systemic Lupus ...

  14. Images of Sle-7l

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