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  1. Including results for AD-ALCOHOL.
    Do you want results only for AD-ALCMHL?
  2. Alcohol metabolism in alcohol use disorder: a potential ...

  3. A common East-Asian - Nature

  4. People also ask
    AD-9308 is a water-soluble, potent, and highly selective ALDH2 activator. AD-9308 treatment ameliorates diet-induced obesity and fatty liver, and improves glucose homeostasis in both male Aldh2 wild-type and knock-in mice. Our data highlight the therapeutic potential of reducing toxic aldehyde levels by activating ALDH2 for metabolic diseases.
    Accordingly, the buildup of AcH in people with this variant after ethanol consumption leads to aversive effects such as nausea, headache, and palpitations, which are thought to contribute to the 4-fold decrease in AUD risk for carriers of the ALDH2 polymorphism ( Yang et al. 2010, Wang et al. 2021 ).
    Due to the unpleasant symptoms after ethanol consumption, ALDH2 -deficient individuals are at lower risk of developing alcohol-related diseases and therefore, therapeutics that inhibit ALDH2 have been of interest in the treatment of AUD ( Wang et al. 2020 ).
    ANS-6637 (originally CVT-10216), a selective and reversible ALDH2 inhibitor, showed clear efficacy in preclinical models of alcohol consumption and has since been developed as an orally active treatment for AUD by Amygdala Neurosciences, Inc. ( Arolfo et al. 2009 ).
  5. Interactions between the metabolic syndrome and alcohol ...

  6. Binge drinking is a growing public health crisis − a ...

  7. Alcohol consumption and the risk of all-cause and cause ...

  8. Changes in alcohol consumption and alcohol problems before ...

  9. 8 Of The Healthiest Alcoholic Drinks & How To Enjoy Them ...

  10. Alcohol use: Weighing risks and benefits - Mayo Clinic

  11. How much alcohol is too much? Safety tips for summer drinking.

  12. How Alcohol Abuse Affects ADHD - Alcohol Rehab Guide

  13. Including results for AD-ALCOHOL.
    Do you want results only for AD-ALCMHL?
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