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  1. What is Wegener's Disease?

    Answered by verified global health professionals

    Dr. Anet Varghese

    Dr. Anet Varghese community pageDoctor of Medicine (MBBS) · 1 years of expWegener's granulomatosis is an organ- and/or life-threatening autoimmune disease of as yet unknown etiology. T...Read more
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  2. Wegener's granulomatosis

    Also known as: granulomatosis with polyangiitis
    Content medically reviewed by
    Dr. Pawan Kattiverified specialist
    M.S., M.Ch., F.MAS, Urology
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    Symptoms
    If you or someone you know is exhibiting symptoms of Wegener's granulomatosis, seek medical attention immediately.

    Symptoms usually begin with respiratory infections and vary depending on the blood vessels of the organ affected. The common symptoms are:

    • Fever
    • Night sweats
    • Loss of appetite
    • Fatigue
    • Weight Loss
    • Eye : Uveitis, Conjuctivitis, Episcleritis, Renal artery occlusiom
    • Ear, nose and throat : Rhinitis, Epitaxis, Otitis media, hearing Loss
    • Lungs : Cough (with blood), Dyspnea, chest discomfort
    • Musculoskeletal : Myalgia, Arthritis, Athralgia
    • Kidney : Renal disease, Renal failure
    • Nervous system : Mononeuritis, sensorimotor polyneuropathy, cranial nerve palsies
    • Cutaneous : Ulcerations, palpable purpura, vesicles, digital necrosis

    Causes

    • It is an autoimmune disorder and the exact cause is unknown.
    • Environmental exposure may triggers autoimmune response

    Complications

    If untreated for a prolonged period it may lead to

    • End-stage renal disease
    • Perforation of the nasal septum
    • Saddle nose deformities
    • Hearing loss
    • Destructive sinus disease
    • Chronic pulmonary dysfunction
    • Proptosis
    • Blindness

    Source: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
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  3. People also ask
    What is Wegener's granulomatosis?
    Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis. It slows blood flow to some of your organs. The affected tissues can develop areas of inflammation called granulomas, which can affect how these organs work.

    Granulomatosis with polyangiitis - Symptoms and causes

    mayoclinic.org
    What are the symptoms of granulomatosis with polyangiitis?
    The first warning signs usually involve your sinuses, throat or lungs. The condition often worsens rapidly, affecting blood vessels and the organs they supply, such as the kidneys. Signs and symptoms of granulomatosis with polyangiitis might include: For some people, the disease affects only the lungs.

    Granulomatosis with polyangiitis - Symptoms and causes

    mayoclinic.org
    What is Wegener granulomatosis with polyangiitis?
    For many years, granulomatosis with polyangiitis was known as Wegener’s granulomatosis or Wegener granulomatosis. Wegener is the surname of a physician who was one of the first to describe the disorder in detail in the medical literature back in the 1930s. Other doctors before Wegener also described the disease.

    Granulomatosis with Polyangiitis - Symptoms, Causes, Treatment | NORD

    rarediseases.org
    When was Wegener's granulomatosis first presented?
    The full clinical picture was first presented by Friedrich Wegener (1907–1990), a German pathologist, in two reports in 1936 and 1939, leading to the eponymous name Wegener's granulomatosis or Wegener granulomatosis ( English: / ˈvɛɡənər / ).

    Granulomatosis with polyangiitis - Wikipedia

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  4. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/granulo...

    Granulomatosis with polyangiitis - Symptoms and causes

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    Wegener's Disease: Causes, Signs, Symptoms & Prevention
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  5. Wikipedia
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    Granulomatosis with polyangiitis - Wikipedia

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    Granulomatosis with polyangiitis - NHS
    nhs.uk
    Granulomatosis with Polyangiitis | Johns Hopkins Medicine
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  6. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/4757

    Granulomatosis with Polyangiitis (GPA, formerly called ...

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    Wegener's granulomatosis: symptoms, diagnosis, and treatment
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  7. NHS
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    Granulomatosis with polyangiitis - NHS

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  8. Johns Hopkins Vasculitis Center
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  9. Johns Hopkins Medicine
    https://www.hopkinsmedicine.org/.../wegeners-granulomatosis

    Granulomatosis with Polyangiitis | Johns Hopkins Medicine

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  10. Vasculitis Foundation
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    Granulomatosis with Polyangiitis - Vasculitis Foundation

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  11. National Organization for Rare Disorders
    https://rarediseases.org/rare-diseases/granulomatosis...

    Granulomatosis with Polyangiitis - Symptoms, Causes ...

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  12. The Merck Manuals
    https://www.merckmanuals.com/professional/...

    Granulomatosis with Polyangiitis (GPA) - The Merck Manuals

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