WEBAug 12, 2023 · One of their causative genes, CLN10/CtsD, encodes cathepsin D, a major lysosomal protease. Central nervous system (CNS)-specific CtsD-deficient mice exhibit …
WEB3 days ago · Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21. [2] [3] It can …
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WEBAug 12, 2023 · One of their causative genes, CLN10/CtsD, encodes cathepsin D, a major lysosomal protease. Central nervous system (CNS)-specific CtsD -deficient mice exhibit …
WEBJan 22, 2024 · These observations from cellular and mouse models suggest that active STING signalling is a common feature in LSDs, including Sandhoff disease, Fabry …
Safety, Tolerability, and Antitumor Activity of Zipalertinib Among ...
WEBJun 29, 2023 · Zipalertinib (CLN-081, TAS6417) is an oral EGFR tyrosine kinase inhibitor (TKI) with a novel pyrrolopyrimidine scaffold leading to enhanced selectivity for EGFR …
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