Systemic Lupus Erythematosus - StatPearls - NCBI Bookshelf
WebAug 4, 2023 · HHS. USA.gov. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement.
Systemic lupus erythematosus | Radiology Reference Article ...
WebApr 4, 2024 · Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. Although abnormalities in almost every aspect of the immune system have been found, the key defect is thought …
Systemic lupus erythematosus (musculoskeletal manifestations)
WebApr 9, 2024 · Musculoskeletal manifestations in patients with systemic lupus erythematosus are common and often symptomatic. Characteristic manifestations are seen in approximately 80% of patients, but many less characteristic manifestations are …
Systemic lupus erythematosus - The Lancet
WebApr 17, 2024 · Seminar. Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs such as skin, joints, and kidneys. Despite substantial advances in the diagnosis and …
Distinct transcriptomes and autocrine cytokines underpin ... - Nature
WebMar 1, 2024 · Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple autoantibody types, some of which are produced by long-lived plasma cells (LLPC). Active SLE generates...
Physician global assessment for type 2 manifestations of systemic …
WebFeb 2, 2024 · Systemic lupus erythematosus (SLE) manifestations are categorized as type 1 (classic signs and inflammatory symptoms) and type 2 (including symptoms of fatigue, depression, widespread pain, and brain fog). The type 2 manifestations, substantially impacting the quality of life, are reported more frequently by people living …
Vascular damage in systemic lupus erythematosus - Nature
WebJan 3, 2024 · Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease that is associated with a high incidence of cardiovascular disease (CVD). Inflammation related to autoimmunity promotes...
Current treatment of systemic lupus erythematosus: a clinician's ...
WebMay 12, 2023 · Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Its variable course makes it difficult to standardize patient treatment. This article aims at a literature review on available drugs for treating SLE and on drugs that have shown therapeutic effects in this disease.
Systemic lupus erythematosus (SLE) – GPnotebook
WebLast edited 28 Oct 2023. Authoring team. Systemic lupus erythematosus is the classic prototype of a chronic, multisystem, inflammatory connective tissue disorder of autoimmune origin (1,2). often follows a relapsing and remitting pattern (3)
PD-L1- and IL-4-expressing basophils promote pathogenic
WebApr 22, 2024 · Nature Communications - Basophils have been implicated in systemic lupus erythematosus (SLE), as evidenced by the fact that basophil-deficient mice do not develop the disease. Here, the...
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