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    The MTRR gene provides instructions for making an enzyme called methionine synthase reductase. Learn about this gene and related health conditions.
    Methionine synthase reductase (MTRR) is primarily involved in the reductive methylation of homocysteine to methionine, utilizing methylcob (I)alamin as an intermediate methyl carrier. Methionine is an essential amino acid in mammals, necessary for protein synthesis and one carbon metabolism.
    en.wikipedia.org
    Diseases associated with MTRR include Homocystinuria-Megaloblastic Anemia, Cble Complementation Type and Neural Tube Defects, Folate-Sensitive . Among its related pathways are Cobalamin (Cbl, vitamin B12) transport and metabolism and Metapathway biotransformation Phase I and II .
    The MTR (methionine synthase) gene and the MTRR (methionine synthase reductase) gene both code for enzymes that are involved in the conversion of homocysteine to methionine. They are essential players in the methylation cycle. This article explains where the MTR and MTRR genes fit within the methylation cycle.
  2. MTRR gene: MedlinePlus Genetics

  3. MTRR (gene) - Wikipedia

  4. MTR and MTRR Genes: Methylation cycle and the need …

    WebNov 19, 2018 · Learn how the MTR and MTRR genes code for enzymes that convert homocysteine to methionine using methyl-B12. Find out how …

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