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  1. Studies of MM-HSPA9
  2. HSPA9 reduction exacerbates symptoms and cell death in ...

  3. HSPA9/mortalin inhibition disrupts erythroid maturation ...

  4. People also ask
    HSPA9 is predominantly present in mitochondria and is essential in mitochondrial processes, including protein import, folding, and degradation. Additionally, it participates in the regulation of the oxidative stress response, mitochondrial membrane potential, energy generation, and intracellular transport 9, 10.
    Thus, it has been implicated in various cellular functions, including stress response, cell proliferation control, and apoptosis inhibition. In particular, HSPA9 regulates the functions of the tumor suppressor protein p53 and plays an important role in the stress response and maintenance of the mitochondria [ 17, 27 ].
    HSPA9, a member of the heat shock protein 70 family, plays a crucial role in regulating mitochondrial processes and responding to oxidative stress. HSPA9 deficiency disrupts mitochondrial dynamics, increasing mitochondrial fission and the production of reactive oxygen species.
    HSPA9 is primarily localized to the mitochondria and is involved in multiple mitochondrial processes, including energy metabolism, free-radical generation, and maintenance of mitochondrial protein integrity [ 15 ]. However, the role of HSPA9 in cilia has not been elucidated.
  5. Abstract 248: HSPA9/mortalin regulates erythroid maturation ...

  6. Single-cell transcriptional profiling of hearts during cardiac ...

  7. Enhanced primary ciliogenesis via mitochondrial oxidative ...

  8. Human HSP70-escort protein 1 (hHep1) interacts with ...

  9. [PDF] HSPA9 reduction exacerbates symptoms and cell ...

  10. Europe PMC

  11. A cytosolic surveillance mechanism activates the ...

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